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Scientists try to grow Covid vaccine-filled spinach, lettuce, edible plants to replace Covid injections

Millions of people who refused to get an experimental mRNA vaccine may soon be forced to use the gene therapy in their food.

Researchers at the University of California have received a $ 500,000 grant from the National Science Foundation, which is developing technology that infuses experimental mRNA Covid-19 vaccines into spinach, lettuce and other edible plants.

The team of nanobiotechnology experts is currently working to successfully deliver DNA containing mRNA BioNTech technology in chloroplasts, the part of the plants that are instructed by its cells’ DNA to replicate the vaccine material.

The researchers have the task of demonstrating that the genetically modified plants can produce enough mRNA to replace Covid stimuli and fill in the plants with the right dose needed to eat to replace vaccines.

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Experimental mRNA vaccines will be edible, Juan Pablo Giraldo, an associate professor in UCR’s Department of Plant and Plant Sciences who leads the research explained in a press release release published on September 16 by the university.

“Ideally, a single plant would produce enough mRNA to inoculate a single person,” Giraldo said. “We are testing this approach with spinach and lettuce and have long-term goals for people to grow it in their own gardens,”

“Farmers can also eventually cultivate entire fields from it,” he added.

To effectively deliver the genetic material to a plant’s chloroplast, small organs in plant cells that convert sunlight into energy that the plant can use are critical to rolling out the vaccinated food.

“[Chloroplasts are] “Small, solar-powered factories that produce sugar and other molecules that allow the plant to grow,” Giraldo said. “They are also an untapped source for making desired molecules.”

Genetically modifying edible plants with experimental vaccines for public consumption is the pinnacle of a dream, the associate professor explained.

“One of the reasons why I started working in nanotechnology was so that I could apply it to plants and create new technology solutions. Not only for food, but also for high-value products, such as pharmaceuticals, ”he said.

While previous studies have shown that chloroplasts are unable to express genes that are not a natural part of that plant, Giraldo’s team sends genetic material inside a protective envelope in plant cells. To bring about the unprecedented genetic therapy, Giraldo recruited Nicole Steinmetz, a UC San Diego professor of nano-engineering.

Steinmetz is working with Giraldo’s team to use nanotechnologies that allow a plant’s chloroplast to be administered with the mRNA vaccine.

“Our idea is to reuse naturally occurring nanoparticles, namely plant viruses, for gene delivery to plants,” Steinmetz said. “Some engineering goes into this to let the nanoparticles go to the chloroplasts and also to make them non-infectious to the plants.”

In addition, the National Science Foundation has granted Giraldo and his colleagues $ 1.6 million to develop “targeted nitrogen delivery,” technology that uses nanomaterials to deliver nitrogen, a fertilizer, directly to chloroplasts.

Meanwhile, more people are dying from the COVID-19 “vaccine” than any other vaccine in recorded history. According to the CDC’s Vaccine Adverse Event Reporting System, 18,409 people died from vaccination in 2021, while only 420 people died from vaccination before Covid vaccination mandates in 2020.

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